JASCO P-4000 Series Polarimeters are advanced analytical instruments designed to deliver high-precision optical rotation measurements while meeting the demanding requirements of today’s pharmaceutical, chemical, and research laboratories. Engineered with a strong focus on pharmacopoeia compliance, data integrity, and user-friendly operation, the P-4000 Series combines cutting-edge technology with a compact, space-saving design.
A key advantage of the P-4000 Series is its exceptional accuracy and stability in optical rotation measurement, including the determination of specific rotation [α]D, which is widely required in pharmaceutical analysis. The instruments support multiple light sources—including Sodium, Mercury, LED, and Tungsten lamps—offering maximum flexibility across a wide range of applications.
Complemented by a wide range of dedicated accessories, including innovative rectangular quartz cells for small-volume samples and automated sampling solutions, the JASCO P-4000 Series stands out as a complete, future-proof polarimetry solution.
Designed for long-term reliability, the P-4000 Series offers excellent resistance to acidic samples. Protective coatings, fluororesin-treated sensors, sealed optical windows, and built-in exhaust systems prevent instrument degradation and extend operational lifespan, even in harsh chemical environments.
Sample temperature control is another critical feature built into the P-4000 Series as standard. Using advanced Peltier temperature control technology and direct sample temperature monitoring, the system ensures stable and reproducible measurement conditions. The automatic measurement start function activates analysis only when the target temperature is reached, improving efficiency and minimizing operator error—an essential benefit for regulated laboratories.
For fast measurement, the P-4000 series has a response speed of up to 6° per second, with an outstanding 4-digit resolution of 0.0001°. The wide dynamic range up to ±90° enables measurement over a very broad range of concentrations.
Validation and performance verification are streamlined through guided validation and daily check programs. Using Certified Quartz Control Plates, laboratories can easily verify accuracy, repeatability, linearity, and temperature control in accordance with pharmacopoeia requirements. This simplifies compliance while reducing downtime.
For laboratories operating under regulatory frameworks such as 21 CFR Part 11, the P-4000 Series offers advanced data management and security features. User access control, audit trails, electronic signatures, automated backups, and seamless LIMS integration ensure full data integrity in line with ALCOA+ principles
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